<<< Ingredients & Their Benefits >>>

1. Grape Seed Extract


1. Its antioxidant property exerts a strong oxygen free radical-scavenging effect and exerted a beneficial impact on blood pressure.
2. Shows anti-inflammatory, anti-apoptotic, anti-necrotic, cardiovascular and anti-carcinogenic activity.
3. Has a direct follow up on the prevention of CVD due to its polyphenol content which averts radical oxidation of the PUFA of LDL (Rimm et al. 1993).
4. Capable to reduce the risk of CVD by inhibiting the oxidation of LDL, improving endothelial function.
5. Inhibiting of platelet aggregation, reducing inflammation, lowering blood pressure and prevent cell senescence by activating novel proteins (Dohadwala and Vita 2009).
5. Significantly reduces oxidized LDL. Bagchi et al. and cardiac dysfunction and improved the pathological changes due to MI injury.

2. Resveratrol Extract


1. Potential anti-atherosclerotic agent with antioxidant and anti-inflammatory properties.
2. Stimulates endothelial NO synthase which is crucial for regulating and maintaining a healthy cardiovascular system.
3. Protects the vascular walls from oxidation, inflammation, platelet aggregation, and thrombus formation hence, prevents cardiac tissue damage.
4. Aid in inhibiting the migration and proliferation of vascular smooth muscle cells and decrease the risk of vascular disorders.
5. May attenuate high pressure and prevent cardiac hypertrophy in hypertensive conditions.

3. Fenugreek Extract


1. Shown to exert antioxidant activity that could have a protective role against cardiovascular disease in diabetes.
2. The effect of fennel-derived nitrites on angiogenesis (the formation of new blood vessels from pre-existing ones), cell migration, and vasorelaxation (dilation of blood vessels) preserves cardiovascular health.

4. Ginkgo Biloba Extract


1. It is of great significance to control the impaired glucose regulation and slow down the development of diabetes and reduce the incidence and mortality of cardiovascular diseases.
2. Demonstrated to promote recovery after stroke.
3. Shown to exert potential physiological effects on thrombosis, i.e. platelet function and endothelial function.

5. Pterostilbene (Pterocarpus marsupium extract)


1. Its antioxidant activity may play an important role in the cardioprotective effects.
2. Demonstrated protective benefits against atherosclerosis through the regulation of vascular smooth muscle cells (VSMCs) and vascular endothelial cells (VECs).

6. Policosanol Extract


1. A mixture of alcohols isolated and purified from sugar cane.
2. Shown to have performed equal to or better than simvastatin, pravastatin, lovastatin, probucol, or acipimox with fewer side effects in patients with type II hypercholesterolemia.
3. Decreases several other risk factors of cardiovascular disease by decreasing LDL oxidation, platelet aggregation, endothelial damage, and smooth muscle cell proliferation.

7. Phytosterols Extract


Plant-origin bioactive compounds that exerts reducing effect of LDL-cholesterol and may confer cardiovascular protection. Arq. Bras. Cardiol. 109 (5) • Nov 2017

8. Garlic Extract


Garlic in combination with fenugreek would be beneficial under hypercholesterolemic conditions by their influence on the tissue lipid profile.

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